Definition and Introduction

  • Biosafety is the prevention of risk to human health and safety, and the conservation of the environment and the pathogen, as a result of the use for research and commerce of infectious or genetically modified organisms.
  • These levels are defined by the Central for Disease Control and Prevention (CDC), where each of these levels is outlined with specific practices and safety requirements.
  • As per the CDC, biosafety levels are of four types depending on the risk associated with the microorganism and the facilities available. The levels of containment range from the biosafety level 1 (BSL-1), which is the lowest to the level 4 (BSL-4), which is the highest.

Source pic : https://consteril.com/biosafety-levels-difference/

Biosafety Levels

1. Biosafety Level -1 (BSL-1)

  • Biosafety Level 1 is the level appropriate for work involving well-characterized agents not known to consistently cause disease in immune-competent adult humans and cause a minimal potential hazard to the laboratory personnel and the environment

2. Biosafety Level -1 (BSL-1)

  • Biosafety level-2 laboratories are the laboratories that are used for the tasks involving microbial agents of moderate potential hazards to the laboratory personnel, the environment, and the agent.

3. Biosafety Level-3 (BSL-3)

  • Biosafety level 3 (BSL-3) is the level where work is performed with agents that may cause severe or potentially lethal disease through inhalation or aerosol formation, to the personnel, and may even contaminate the environment.

4. Biosafety Level 4 (BSL-4)

  • Biosafety level 4 is the highest level that is employed while working with dangerous infectious agents that present a high individual as well as environmental risk in the form of life-threatening disease, aerosol transmission, or unknown risk of transmission.

Source :
https://microbenotes.com/biosafety-levels/#definition-and-introduction